Through difficult technical research, the research team of Zhongguancun Huakang Gene Research Institute recently successfully developed a new generation of pathogenic gene detection technology with high accuracy, low cost and high efficiency, and successfully tested a variety of genetic diseases clinically And prevention were applied.

Experts pointed out that the breakthrough and preliminary clinical application of this technology have created the possibility of large-scale, multi-disciplinary clinical promotion of genetic testing technology.

Gene refers to a DNA sequence that carries genetic information. Genetic testing is a technique for detecting DNA through blood, other body fluids or cells. With genetic testing, early diagnosis, early evaluation, early prevention and early treatment of genetic diseases can be carried out. At present, there are more than a thousand genetic diseases that can be diagnosed by first-generation sequencing, gene chip, ordinary high-throughput sequencing and other genetic testing technologies.

In recent years, the scientific research team of Zhongguancun Huakang Gene Research Institute has used a new generation of disease-causing gene detection technology for the purpose of solving clinical problems, genetically quantifying dozens of families and hundreds of patients with genetic cardiovascular diseases and tumor Screening, and on the basis of information on gene mutations, provide genetic counseling on individual patient treatment, prevention of dangerous clinical events and family screening, eugenics and eugenics.

Compared with the three mainstream detection technologies of first-generation sequencing technology, gene chip technology, and ordinary high-throughput sequencing technology, the new generation of pathogenic gene detection technology has certain advantages in accuracy, economy, and efficiency. The application of a new generation of detection technology can not only detect common known disease-causing genes, but also detect hundreds of related possible disease-causing genes at the same time, reducing the rate of missed diagnosis and providing an effective means for discovering new disease-causing genes.

The breakthrough of low-cost pathogenic gene detection technology has attracted the attention of the medical community. Zhongguancun Huakang Gene Research Institute has signed scientific research cooperation agreements with Beijing Tiantan Hospital, Beijing Cancer Hospital, Fuwai Cardiovascular Hospital of the Chinese Academy of Medical Sciences, and the Institute of Sports Medicine of the State Sports General Administration. Pathogenic gene detection technology, to jointly carry out scientific research and clinical application on the detection of genetic genes of various systemic genetic diseases, the prevention of sudden exercise death and eugenics.

Wei Wei, Dean of the Zhongguancun Huakang Gene Research Institute, said that with this technology, we have the possibility to build the largest gene technology research and application platform in China and the world under the translational medicine model. In the next step, we will cooperate with more hospitals and regions to apply this technology to the clinic as soon as possible. At the same time, a public service platform for genetic testing will be established to provide technical support for clinical and scientific research work of various medical and scientific research institutions.

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